A 2006 study in the British Journal of Dermatology identified sebum output as the strongest modifiable factor in pore size, while a 2025 review in Frontiers in Genetics confirmed that baseline pore size is a polygenic trait determined by hundreds of interacting genes. The takeaway: you can't change your genetics, but you can significantly minimize how visible your pores appear.
Quick Summary:
- Pore size is primarily determined by genetics — you can't permanently shrink pores smaller than your DNA allows
- Sebum production is the strongest controllable factor affecting how large pores look
- Retinoids reduce visible pore size by 20-37% in clinical studies after 12-24 weeks
- Niacinamide at 2-4% decreases sebum output and improves pore appearance within 8-12 weeks
- Daily sunscreen prevents the collagen loss that makes pores enlarge with age
What Causes Large Pores
Pores are the openings of hair follicles on your skin's surface, and their size depends on several factors working together.
Genetics: The single biggest determinant of pore size. A 2025 review in Frontiers in Genetics found that pore size and number are polygenic traits similar to height — determined by specific sequences of hundreds of interacting genes. The production, maintenance, and degradation of collagen alone involves over 60 genes.
Sebum production: Research in the British Journal of Dermatology confirmed that sebum output level correlated most strongly with pore size among all modifiable variables. Males showed a particularly strong correlation (r = 0.47), driven by androgen levels. In women, the relationship varies with the menstrual cycle, with pore size increasing during ovulation.
Aging and collagen loss: Collagen and elastin provide structural support for pore walls. As these proteins decrease with age — about 1% per year after your mid-20s — pore openings lose their framework and appear wider. This is why pores that were barely visible in your teens can become prominent in your 30s and 40s.
Sun damage: UV radiation destroys collagen and elastin through increased matrix metalloproteinases (MMPs). Chronic sun exposure causes skin to sag around pore openings, creating a stretched appearance. This is why enlarged pores often cluster on sun-exposed areas like the nose, cheeks, and temples.
Can You Actually Shrink Pores?
Let's be clear: no product can permanently reduce your pores to a size smaller than your genetics allow. Marketing that promises to "close" or "eliminate" pores is misleading.
What treatments can do is minimize how visible pores appear by addressing the controllable factors — excess sebum, debris accumulation, and collagen loss. Clinical studies show 20-37% improvement in visible pore size with consistent treatment, which translates to a noticeable difference in skin appearance.

Ingredients That Minimize Pore Appearance
Retinoids: The Strongest Evidence
Retinoids address enlarged pores through two mechanisms: normalizing follicular cell shedding (so pores don't fill with dead cells and stretch) and stimulating collagen production (restoring structural support around pore walls).
A clinical study found that retinol reduced pore dilation by 30.6% after 84 days, while tretinoin achieved 37.5% reduction over the same period. A separate trial showed pore improvement of 22% at 8 weeks and 23% at 12 weeks with a retinoid cream.
For over-the-counter options, start with The Ordinary Retinol 0.5% in Squalane (around $7) two to three nights per week. See our retinol guide for the full introduction protocol.
Niacinamide: Sebum Control
A randomized, double-blind, placebo-controlled study of 52 subjects found significant reductions in pore counts at weeks 8 and 12 when using 4% niacinamide. Separate research showed that 2% niacinamide effectively lowers sebum excretion rates.
Niacinamide works indirectly — by controlling oil production and improving overall skin function, it minimizes how prominent pores appear. The Ordinary Niacinamide 10% + Zinc 1% (around $7) provides both niacinamide for sebum control and zinc for additional oil regulation.
Salicylic Acid: Pore Clearing
Salicylic acid is oil-soluble, meaning it can penetrate into pores to dissolve the sebum and dead cell buildup that stretches them open. Regular use keeps pores clear, reducing their visible size. Paula's Choice 2% BHA Liquid Exfoliant (around $33) is a well-formulated option. Use two to three times weekly.
Verdict: The most effective approach to minimizing large pores combines three strategies: retinoids for collagen support and cell turnover, niacinamide for sebum control, and salicylic acid for keeping pores clear. No single product will do it all, but this combination addresses every controllable factor.
Building a Pore-Minimizing Routine
Morning:
- Gentle cleanser
- Niacinamide serum
- Lightweight moisturizer
- Broad-spectrum sunscreen SPF 30+ — EltaMD UV Clear SPF 46 (around $40) is formulated with niacinamide and won't clog pores
Evening:
- Oil-based cleanser or micellar water (if wearing sunscreen/makeup)
- Gentle cleanser
- Retinol (2-3 nights per week) or BHA exfoliant (alternate nights)
- Moisturizer
For a complete routine framework, see our building a skincare routine guide.

What Doesn't Work
Pore strips: They pull out the surface of sebaceous filaments but don't change pore size. The filaments refill within 24-48 hours. They can also damage the skin around pores, worsening appearance over time.
Ice or cold water: Temporarily constricts the skin around pores, creating the illusion of smaller pores that lasts minutes. No lasting benefit.
Heavy mattifying products: Silicone-based primers fill pores cosmetically but don't treat the underlying causes. Some heavy formulations can actually clog pores and make them appear larger over time.
Alcohol-based toners: Strip oil temporarily but trigger rebound sebum production that makes pores look worse within hours. Stick to alcohol-free formulations.
When to See a Dermatologist
If over-the-counter products aren't delivering enough improvement after three to four months of consistent use, a dermatologist can offer stronger options:
- Prescription tretinoin (0.025-0.1%) delivers stronger results than OTC retinol
- Laser treatments including picosecond lasers have shown moderate to significant improvement in clinical trials
- Professional chemical peels with higher acid concentrations than home-use products
- Combination therapy using multiple professional treatments alongside topical ingredients achieves the best outcomes — one study reported 93.3% patient satisfaction with a triple treatment approach
Frequently Asked Questions
Can pores permanently shrink?
Pores cannot shrink smaller than your genetic baseline. Treatments minimize their appearance by addressing sebum production, collagen loss, and debris buildup. Continued treatment is necessary to maintain results.
Why are my pores bigger on my nose?
The nose has the highest density of sebaceous glands on the face, producing more oil than any other area. Higher sebum output directly correlates with larger pore appearance. What many people think are "blackheads" on their nose are actually sebaceous filaments — a normal feature of oily skin.
Does oily skin mean larger pores?
Research confirms a strong correlation. Sebum output is the most significant modifiable factor in pore size. Managing oil production with niacinamide and salicylic acid helps reduce pore visibility. See our oily skin guide for a full routine.
Can moisturizer make pores look smaller?
Properly hydrated skin appears plumper and smoother, which can make pores less noticeable. Dehydrated skin looks more textured, amplifying the appearance of pores. Use a lightweight, non-comedogenic moisturizer that won't clog pores.
Do pores get bigger with age?
Yes. As collagen and elastin decrease, the structural support around pore walls weakens and openings widen. This is why sun protection is critical — UV damage accelerates collagen breakdown and directly contributes to pore enlargement over time.
How long do pore-minimizing products take to work?
Niacinamide shows results in 8-12 weeks. Retinoids improve pore appearance measurably at 8-12 weeks, with continued improvement up to 24 weeks. Salicylic acid works faster for clearing pore congestion — within 4-6 weeks — but doesn't address the structural factors.
Is it better to use retinol or niacinamide for pores?
Both, as they address different factors. Niacinamide controls sebum and oil. Retinol stimulates collagen and normalizes cell turnover. Using niacinamide in the morning and retinol at night targets pores from both angles.
Can makeup cause enlarged pores?
Makeup itself doesn't enlarge pores, but not properly removing it can. Leaving makeup in pores overnight allows it to mix with sebum and dead cells, stretching pore openings over time. Always cleanse thoroughly at night — consider double cleansing if you wear heavy makeup or sunscreen.
Do pore-minimizing primers actually help?
Silicone-based primers create a temporary smooth appearance by physically filling pore openings, but they don't treat any underlying cause. They're fine for cosmetic use but shouldn't replace an actual treatment routine.
What's the difference between pores and acne scars?
Pores are natural follicular openings present across your entire face. Acne scars (ice pick, boxcar, rolling) are tissue damage from inflammatory breakouts, usually appearing as irregular depressions in areas where acne was severe. Pores are uniform and round; scars are irregularly shaped.
Does diet affect pore size?
No direct clinical evidence links specific foods to pore size. However, high-glycemic diets increase insulin and androgen levels, which boost sebum production. Reducing processed sugars and dairy may indirectly help by decreasing oil output, though the evidence is stronger for acne than for pore size specifically.
The Bottom Line
Large pores are primarily genetic, but their appearance is controllable. A consistent routine combining retinoids for collagen support, niacinamide for oil control, and salicylic acid for pore clearing delivers measurable improvement within 8-12 weeks. Add daily sunscreen to prevent the collagen loss that worsens pores over time.
Sources:
- Roh M, Han M, Kim D, Chung K. Sebum output as a factor contributing to the size of facial pores. Br J Dermatol. 2006;155(5):890-894. https://pubmed.ncbi.nlm.nih.gov/17034515/
- Chiu PC, Chan CC, et al. The clinical anti-aging effects of topical kinetin and niacinamide in Asians. J Dermatol Sci. 2007;48(3):203-210. https://pubmed.ncbi.nlm.nih.gov/18047609/
- Parvar S, Bayat M, Rezaee E. The efficacy and adverse effects of treatment options for facial pores: A review. J Cosmet Dermatol. 2023. https://pubmed.ncbi.nlm.nih.gov/36440737/
- McDaniel DH, et al. Efficacy and tolerability of a double-conjugated retinoid cream. J Cosmet Dermatol. 2017. https://onlinelibrary.wiley.com/doi/10.1111/jocd.12381
- Genetic profiling and precision skin care: a review. Front Genet. 2025. https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2025.1559510/full